INHERITED 15Q DUPLICATION IN THREE NOT RELATED UKRAINIAN FAMILIES
Background.15q duplication syndrome (Dup15q) is caused by the presence of an extra maternally derived copy of the Prader-Willi/Angelman critical region (PWACR) within chromosome 15q11.2-q13.1.The syndrome is clinically identifiable and characterized by intellectual disability, hypotonia, motor delays, Parts autism spectrum disorder, epilepsy, and b